E-Book

E-Book 3rd Congress

  • Iranian herbal medicines used for therapy of diabetes mellitus: a systematic review of the pharmacological aspects
  • Hadis Rahimi,1 Shadi Nazarifard,2 Fatemeh Ahmadpour,3,*
    1. Student research committee, Lorestan University of Medical Sciences, Khorramabad, Iran
    2. Student research committee, Lorestan University of Medical Sciences, Khorramabad, Iran
    3. Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran


  • Introduction: Background and Aim: Medicinal plants play an important role in the treatment of diabetes mellitus, especially in the developing countries due to their cost effectiveness. Diabetes mellitus, a metabolic disorder, is becoming a serious threat to mankind health. The prevalence of diabetes mellitus is expected to reach up to 4.4% in the world by 2030. Among all type of diabetes, type 2 diabetes is main complication. Currently available treatment options in modern medicine have several adverse effects. Therefore, there is a need to develop safe and effective treatment modalities for diabetes.
  • Methods: Methods: This systematic review presents the profiles of plants with hypoglycemic/anti diabetic properties reported in the literature from 2010 to 2022. The relevant keywords were searched from Google Scholar, Pub Med, Science direct, Cochrane library and EMBASE databases.
  • Results: Results: Various plants have been found to possess significant anti-diabetic property after their preclinical and clinical evaluation. Use of these plants may delay the development of diabetic complications and can correct the metabolic abnormalities through variety of mechanisms. Moreover, during the past few years many phytoconstituents responsible for anti-diabetic effects have been isolated from plants.
  • Conclusion: Conclusion: This review demonstrates the limitations in published articles of human clinical trials for medicinal plants’ intervention for diabetes. Upon further investigations on the identified medicinal plants included in the animal studies, the findings showed positive effects in the management of diabetes, such as hyperglycemia. Hence, further testing and standardization of the methods in the studies can be suggested for human clinical trials for reliable data collections such as methods of extract preparation, duration of intervention, and conditions set for the study design.
  • Keywords: Diabetes mellitus, Herbal medicine, Glycemic index