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E-Book 3rd Congress

  • The science behind probiotic bacteria isolated from honey samples and their effect on lipid profiles Review article
  • Haniye Fayezi,1,*
    1. M.sc student of Pathogenic Microbes Islamic Azad University North Tehran Branch


  • Introduction: Probiotics are live microorganisms that, when consumed in adequate amounts, confer health benefits to the host. These beneficial bacteria are commonly found in fermented foods and can also be taken as supplements. Probiotics play a crucial role in maintaining the balance of our gut microbiota, which has a far-reaching impact on our overall health. Bacteria isolated from honey samples contain bacterial strains that show probiotic potential. Natural honey can help increase HDL and lower LDL cholesterol levels, as well as reduce the risk of cardiovascular disease. Elevated triglyceride levels are another significant contributor to an unhealthy lipid profile. Excessive triglycerides in the blood can increase the risk of heart disease and stroke. The good news is that natural honey has been shown to help regulate triglyceride levels, keeping them within a healthy range and promoting a balanced lipid profile.
  • Methods: While the exact mechanisms behind honey's impact on lipid profiles are not yet fully understood, researchers believe that its antioxidant and anti-inflammatory properties play a significant role. Antioxidants help reduce oxidative stress and inflammation in the body, which are key factors in the development of cardiovascular diseases. Probiotics can change the composition of bile acids, which increases cholesterol metabolism and decreases cholesterol, reducing the total cholesterol burden of the body.
  • Results: Several scientific studies have been conducted to evaluate the effectiveness of isolates in honey to reduce cholesterol levels. These studies show promising results that may indicate that some probiotic strains in honey can help lower cholesterol. Administering specific bacterial strains from honey samples led to a significant reduction in total cholesterol and LDL cholesterol levels in mice. Similar findings were observed in human studies, suggesting the potential application of these results in humans. Research is needed to determine optimal strains, dose, and duration of treatment. In addition, the effectiveness of these probiotics may vary among individuals for reasons in the composition of the gut microbiota. It is important to check with a healthcare professional before introducing probiotics into your diet, especially if you have a medical condition that requires you to take medications that could interact with these supplements.
  • Conclusion: With its potential to reduce LDL cholesterol, increase HDL cholesterol, and regulate triglyceride levels, incorporating natural honey into diet may contribute to a healthier lipid profile. The evaluation of different bacterial honey isolates as probiotics and their efficient roles in cholesterol reduction is an intriguing field of study. Scientific evidence suggests that certain strains present in bacterial honey isolates can positively influence cholesterol levels through various mechanisms. While further research is needed to fully understand the optimal use of these probiotics, their potential in promoting cholesterol reduction offers hope for individuals seeking natural ways to improve their cardiovascular health.
  • Keywords: Honey; Probiotics; Cholesterol; Cardiovascular disease