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  • Examining the titer of antibodies against surface and central antigens of hepatitis B virus among students of Dezful University of Medical Sciences
  • Behnam Azizolahi,1,* Susan Sabbagh,2 Alireza Khosropanah,3 Mohsen Piramoon,4 -,6
    1. Department of Medical Laboratory Sciences, School of Paramedicine, Dezful University of Medical Sciences, Dezful, Iran
    2. Department of anatomical science, School of medicine, Dezful University of Medical Sciences, Dezful, Iran.
    3. Department of internal Medicine, School of medicine, Dezful University of Medical Sciences, Dezful, Iran.
    4. Student Research Committee, Dezful University of Medical Sciences, Dezful, Iran
    6. -


  • Introduction: Introduction: Hepatitis B disease is one of the diseases that has been a serious threat to the health of health care workers. Therefore, this study aims to investigate the titer of antibodies against surface and central antigens of hepatitis B virus among students of Dezful University of Medical Sciences in the academic year of 1401.
  • Methods: Methods: This is a cross-sectional descriptive epidemiological study that was conducted on 331 students of Dezful University of Medical Sciences who need to enter hospital departments for internships in the future. At first, the demographic information included gender, field and level of education were taken. In order to determine the antibody titer against the s antigen of the virus, commercial kits were used by the ELISA method, and to determine the previous infection, the ELISA method kits were used to measure the antibody titer against the c antigen. The obtained results was analyzed by spss software using descriptive statistical methods.
  • Results: Results: The present study was conducted among 188 students of Dezful University of Medical Sciences. 68.6% of them ranged in the age of 21-30 years old, 50.5% were female students, and the distribution of the field of study showed that most of the participating students were medical and nursing students. Regarding HBSAb antibody, 49.5% were weak or unsafe, 45.2% were moderate or acceptable, 5.3% were strong or favorable, and the results also showed that there was a significant relationship between HBSAb antibody titer and age. HBCAb antibody titer was negative in 95.2% of students
  • Conclusion: Conclusion: The results of this study show that half of the students of Dezful University of Medical Sciences do not have adequate immunity to protect against hepatitis B virus infection. Therefore, it is necessary to check the antibody titer of students of medical sciences, especially students of fields that have a high risk of exposure to this virus, and if their antibody titer is low, a reminder vaccine should be prescribed for them
  • Keywords: HBSAb, HBCAb, hepatitis, students.